Riaz Ahmed.
Comparative study of Corticotrophin vs. Vigabatrin therapy in infantile spasm.
Pak J Med Sci Jan ;23(1):141-4.

Twenty six patients were diagnosed as infantile spasm, on the basis of fixed criteria and they were divided into symptomatic (17 patients) and cryptogenic (9 patients) groups according to history, presentation and investigations. Corticotrophin as Tetracosactrin was given to eleven patients and fifteen patients received Vigabatrim (VGB). The response to VGB was significant (73%) compared to steroids (63%), irrespective of the etiology, thus emphasizing that VGB could be considered as the first line therapy for infantile spasm.

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