Maria Adele Giamberardino.
Visceral pain.
Anesth Pain Intens Care Jan ;10(1):38-45.

The recent growth in interest by research, clinicians, and the public in pain originating from internal organs reflects an important paradigm shift. In the past, viscera were considered insensitive to pain, mostly because their responses had not been tested with adequate stimuli. It is now clear that pain from internal organs is widespread and that its social burden may surpass that of pain from superficial (somatic) sources. Credible epidemiological data point to its wide prevalence in various medical conditions, whether organic or dysfunctional, in which it is manifest in acute, recurrent, or chronic form. Moreover, the relatively recent finding of crosstalk between different visceral afferents may account for the apparent diffuse enhancement of pain perception in patients with multiple painful visceral conditions. This is a review article.

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