Bari A U, Zafar Iqbal, Simeen Ber Rahman.
Superficial chemical peeling with salicylic acid in facial Dermatoses.
J Coll Physicians Surg Pak Jan ;17(4):187-90.

Objective: To determine the effectiveness of salicylic acid chemical peeling in common dermatological conditions affecting face in people with predominant Fitzpatrick skin type IV and V. Design: An interventional, quasi-experimental study. Place and Duration of Study: Military Hospital, Rawalpindi and PAF Hospital, Sargodha, from July 2002 to June 2003. Patients and Methods: A total of 167 patients of either gender, aged between 13 to 60 years, having some facial dermatoses (melasma, acne vulgaris, postinflammatory hyperpigmentations, freckles, fine lines and wrinkles, post-inflammatory scars, actinic keratoses, and plane facial warts) were included. A series of eight weekly hospital based peeling sessions was conducted in all patients under standardized conditions with 30% salicylic acid. Clinical improvement in different disorders was evaluated by change in MASI score, decrease in the size of affected area and % reduction in lesions count. McNemar test was applied for data analysis. Results: Majority of the patients showed moderate to excellent response. There was 35% to 63% improvement (p< 0.05) in all dermatoses. Significant side effects, as feared in Asian skins were not observed. Conclusion: Chemical peeling with salicylic acid is an effective and safe treatment modality in many superficial facial dermatoses.

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