Burki M K, Orakzai S A.
The prevalence and pattern of liver disease in infants and children in Hazara Division.
J Ayub Med Coll Abottabad Jan ;13(1):26-8.

BACKGROUND: The pattern of the liver disease may vary in different geographical locations. These reported variations are attributable to the differences in environmental factors, eating habits, socio-economic factors and other reasons. We studied the pattern of liver diseases in infants and children of Hazara Division of Pakistan. METHODS: 200 inpatient and outpatient infants and children in Ayub Teaching Hospital were studied from June, 1998 to October, 1999. RESULTS: The spectrum of defect in the subjects, suffering from liver diseases showed that viral hepatitis was more common (relative frequency of 60%), followed by enteric hepatitis (26%), drug induced liver injury (7.5%), biliary atresia (5.0%) and Criglar-Najjar Syndrome (1.5%). Although both sexes were affected, however, the spectrum of liver disease was more common in males. Moreover, viral hepatitis and enteric hepatitis were found in children aging 6 to 8 years, biliary atresia in 6 months to 2 years, and drug induced liver injury in 3 to 5 years old subjects.

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