Iqbal Hussain Dogar, Bukhari M H, Anjum Mehdi, Muhammad Nawaz Anjum.
Age related changes of vertebral bone mineral density in adult females assessed by quantitative computerized tomography.
Pak Postgrad Med J Jan ;16(4):143-7.

Objective: The study was conducted to assess age related changes of vertebral bone mineral density in adult females by quantitative computerized tomography (QCT). Study Design: This was a descriptive study. Place and Duration of Study: This study was conducted in the Department of Radiology, Children Hospital Lahore from March 2004 to August 2004. Material and Methods: One hundred and twenty five women were included in this study that were divided on age basis into five groups of 25 patients in each. In each age group, the bone mineral density was measured in L2, L3 and L4 by QCT. Results: Peak BMD was seen in adolescents (group 1) 181.18 mg Ca-HA/ml at L-2, 182.6 mg Ca-HA/ml at L-3, and 189.38 mg Ca-HA/ml at L-4. The average BMD of group II at L-2 was 179.97 mg Ca-HA/ml, 180.54 mg Ca-HA/ml at L3 and 183.38 mg Ca-HA/ml at L4. The decline in BMD was noted in group III that was 151.55 mg Ca-HA/ml at L2, 150.22 mg Ca-HA/ml at L3, and 153.07 mg Ca-HA/ml at L4. The rapid decline was noted in group IV which was 123.81 mg Ca-HA/ml at L2, 122.52 mgCa-HA/ml at L3 and 126.39 mg Ca-HA/ml at L4. The further decline in BMD was observed in group V. it was 93.6mgCa-HA/ml at L2, 91.6 mgCA-HA/ml at L3, and 96.05 mgCa-HA/ml at L4. Conclusion: With advancing age there was decrease in bone mineral density (BMD).

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