Bader Faiyaz Zuberi, Masooda Fatima Riaz, Binish Arif Sultan, Parkash Gobindram, Asma Farooq, Rashid Qadeer, Abdul Rauf Memon, Salahuddin Afsar.
Correlation of adjusted blood requirement index with treatment intervention and outcome in patients presenting with acute variceal bleeding.
J Dow Uni Health Sci Jan ;1(2):65-8.

Objective: To determine the correlation of ABRI with treatment intervention and outcome as discharged or expired in patients of acute variceal bleed. Design: Cross-sectional study Patients and Methods: Records of all the patients admitted in Medical Unit-IV, Civil Hospital Karachi with acute variceal bleeding during January 2004 to October 2006 were retrieved. Use of vasoactive agents (Terlipressin/Octreotide), endoscopic band ligation (EBL) and outcome (Discharged/Expired) were noted. ABRI was calculated by the following formula: ABRI = Blood Units Transfused / [(Final Hematocrit - Initial Hematocrit) + 0.01]. Mean ABRI were compared by Student`s `t` test according to vasoactive therapy, EBL and outcome. Correlation of ABRI with the same variables was also studied by plotting Receiver Operative Curves (ROC). Results: Seventy six patients fulfilling inclusion criteria were selected. No statistically significant difference was observed in the mean ABRI scores when compared according to vasoactive drug administration, EBL and outcome. Significant correlation with mortality was seen on ROC plot with significantly larger area under the curve. Conclusion: ABRI correlated significantly with mortality in this study. Larger prospective studies with appropriate power are required to evaluate its association with other variables.

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