Saera Suhail, Muhammad Shakil Baig, Syed Mujahid Humail, Amir Riaz.
Primary Antiphospholipid Antibody Syndrome and autoimmune hemolytic anemia — a rare combination.
J Pak Med Assoc Jan ;59(6):413-4.

Primary Antiphospholipid Antibody Syndrome (PAPS) and Autoimmune haemolytic anemia(AIHA) is a very rare combination. Antiphospholipid Antibody Syndrome (APS) with underlying SLE, however, has a well documented association with Coomb`s positive Auoimmune Haemolytic Anaemia. We describe a young girl with PAPS presenting with deep venous thrombosis, livedo reticularis and features of AIHA. The patient was refractory to treatment for 5 years however, her condition improved dramatically with anticoagulants, corticosteroid therapy and the addition of hydroxychloroquine and azathioprin. We have also discussed hydroxychloroquine therapy in PAPS which is not yet fully established and the probability of this patient developing other autoimmune disorders in future.


USER COMMENTS

does there any association of the two autoimmune disorders or it is just by chance?
Posted by: bvhospital on Jun 2009

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