Abdul Samad, Tariq Wahab Khanzada, Imran Shoukat.
Gastric outlet obstruction: change in etiology.
Pak J Surg Jan ;23(1):29-32.

Objective: To determine the frequency of various aetiologies of Gastric Outlet Obstruction. Design & Duration: Prospective study carried out from July 2000 to September 2006. Setting: Liaquat National Hospital, Karachi and Isra University Hospital, Hyderabad. Patients: All patients who presented with Gastric Outlet Obstruction. Methodology: The data of all the patients who presented with the features of Gastric Outlet Obstruction during the above mentioned period was collected. This data was analyzed with specific reference to recent trends in its aetiology. This change in trend was compared with other local and international studies. Results: Fifty two patients, 25 from Liaquat National Hospital, Karachi and 27 from Isra University Hospital, Hyderabad were included in the study. All patients underwent upper GI endoscopy and biopsy; 40 cases were diagnosed by this method and the remaining by CT scan or laparotomy. Gastric carcinoma was the most common cause of Gastric Outlet Obstruction seen in 35% of the cases. The next common aetiology was peptic ulcer disease which was responsible for 29% of the patients. Conclusion: The ratio between benign and malignant aetiologies of Gastric Outlet Obstruction is showing a gradual change in favour of malignant lesions. This change is similar to the trends reported in the western literature.

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