Bushra Jamil, Syed Faisal Mahmood.
H1N1 2009 in Karachi: a situational analysis.
J Pak Med Assoc Jan ;60(4):250-2.

Karachi saw its first four confirmed cases of novel H1N1 in June 2009. All four were young individuals in their teens and had a history of recent travel to the US, where they developed ILI. The symptoms were mild and they recovered without antiviral treatment. Between June and November, there was only one more case of laboratory confirmed novel H1N1 influenza A. Similar to the prior cases, this 63 year old gentleman, who had presented in August, also had a history of recent travel (this time to Singapore). He made a full recovery after 5 days of Oseltamivir. It is important to note that laboratory diagnosis depends on nucleic acid amplification of H1N1 virus through real time reverse transcriptase polymerase chain reaction (rRT-PCR)9 which is available at two centers in the country: NIH Islamabad and the Aga Khan University Hospital, Karachi. However, most patients with clinical illness consistent with uncomplicated influenza who reside in an area where influenza viruses are circulating do not require diagnostic influenza testing for clinical management. (Editorial)

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