Abida lqbal, Shamim Raza Bokhari.
Status of Rubella IgG antibody in general population at Lahore.
Pak J Pathol Jan ;8(2):37-41.

Four hundred cases from general population ranging from 0-30 years were screened for IgG Rubella antibody using ELSIA technique. The prevalence of antibody increased parallel with increasing age. Infants of 0 age group were sampled along with their mothers for the detection of IgG Rubella antibody at the time of birth. The immune status of infants was similar to their mothers. However, in children of 2-23 months age the seropositivity fell from 88% to 0% at the age of 6 months and remained so till the age of 23 months. In the individuals of 20-39 years of age, the incidence of IgG increased with an increase in age. Individuals of 25-30 years of age had the immune status. 81.78% females of child bearing age (1530) in the present study had immunity to rubella indicative of reasonable immunity against Rubella virus. Increasing antibody prevalence with increasing age in the general population is suggestive of presence of virus in the environment leading to its horizontal transmission.

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