Muhammad Zubair, Aizza Zafar, Hasan Ejaz, Salma Hafeez, Humaira Javaid, Ayisha Javed.
Incidence of coagulase negative staphylococci in neonatal sepsis.
Pak J Med Health Sci Jan ;5(4):716-9.

The aim of the study was to identify the incidence and antimicrobial susceptibility of coagulase negative Staphylococci in neonatal sepsis. This study was carried out in the Children’s Hospital and Institute of Child Health, Lahore, Pakistan during 1st December 2009 to 31st December 2010. A total number of 11541 blood samples from neonates were studied; out of which 388 were positive for coagulase negative Staphylococci. Coagulase negative Staphylococci showed highest susceptibility to vancomycin (97.7%), linezolid (97.4%), amikacin (85.8%) and teicoplanin (73.5%). The less effective antibiotics were co-amoxiclav (68.2%), ciprofloxacin (57.7%), ampicillin (44.6%), ceftriaxone (41.2%), amoxicillin (33.0%), oxacillin (24.2%) and penicillin (16.0%). It was concluded that the vancomycin and linezolid were the best choice of treatment against highly resistant coagulase negative Staphylococci in case of neonatal sepsis.

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