Ghazala Hanif, Mahvish Hussain, Samina Zaman, Anam Shahid, Zonaira Rathore, Saadia Khan, Ayesha Haider.
Pediatric lymphomas: a five year experience at a tertiary care hospital.
Pak J Med Health Sci Jan ;6(1):246-50.

Objectives: To determine the frequency of lymphomas in children in our population and to compare it with national and international studies. Materials and methods: A retrospective analysis was carried out on children under 18 years of age diagnosed with lymphoma in the duration of five years from 2006 till date, at the Histopathology Department of CH & ICH, Lahore. All the cases were re-evaluated and different morphological features were noted. Immunohistochemical stains were applied wherever required. Results: A total of 198 cases of lymphoma were reported. NHL was diagnosed in 70 cases (35.3%). Out of these, lymphoblastic lymphoma were seen in 38 cases (54.28%), whereas 19 cases (27.14%) were of Burkitts lymphoma (BL), 11 cases (15.71%) were of Diffuse Large B Cell Lymphoma (DLBL) type and 1 case (1.42%) each of Anaplastic Large Cell (ALCL) and Follicular Lymphoma. The age range of the cases under study is from 8 months to 16 years with male to female ratio of 2.4: 1. There were 128 (60.3%) cases of Hodgkin’s Lymphoma (HL), among which Mixed Cellularity Type (MC) is more common (n=108, 84.3%). The age range is from 1-14 years with male to female ratio of 9.2:1. Conclusion: Hodgkin Lymphomas of MC Type are far more common than NHL in children with predominance of males.

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