Asghar Ullah Khan, Amir Hamza, Muhammad Frooq Khan, Inayat Ullah Khan.
Clinical presentation of 56 patients of carcinoma larynx admitted at Services Hospital Lahore.
Pak J Med Health Sci Jan ;6(1):59-62.

Objective: To study the presenting clinical features of carcinoma larynx admitted and diagnosed at tertiary care hospital in Lahore. Material and methods: The study was conducted in the Department of ENT head& Neck surgery Lahore from June 2002 to December 2006. Fifty six diagnosed cases of carcinoma larynx were included in the study. A detailed history was taken and a thorough physical examination performed on all patients. All patients were investigated including indirect laryngoscopy/IDL, direct microlaryngoscopy /DL and biopsy for confirmation, CT scan/MRI and findings recorded on proforma. Results: Among 56 patients, 52(92.8%) were male and 4(7.2%) were female. The age ranged between 36-72 years with a mean age of 52.02 years. The majority of patients were between 45-65 years of age. Forty eight patients 85.7%were smokers three of them also used alcohol and 8 (14.2%) patients had a positive family history of laryngeal cancer. The main symptoms were hoarseness/change in voice 52 (-92.86%), foreign body sensation/ globus pharygeous 32(60.7%), strider in 21(37.5%) neck lump 16 patients (28.57%) and Dyspnea in 14(25%), Dysphagia12(21.2%), Throat pain 10(17.85%). Clinically36 patients (64.3% patients presented with stage 1 and 2 and 20(35.7%) with stage 3 and 4 disease. The most common site involved was the glottic region 44.64%, followed by supraglottic 30.35%, transglottic 21.4% and subglottic area 3.57%. Conclusion: Incidence of Carcinoma larynx is significantly higher in male smokers. Hoarseness in smokers should be suspected for cancer of the larynx. Early recognition of carcinoma larynx is a key factor to minimize the mortality and morbidity.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com