Zujaja Zaheer, Samina Kausar, Nisar Ahmed, Nadeem Yaqoob, Sadia Chiragh.
Preventive Effect of Nigella Sativa Essential Oil on Signs of Ocular Allergy Induced by Compound 48/80 in Rabbits.
Pak J Med Health Sci Jan ;6(2):403-5.

Aim: To evaluate preventive anti allergic effect of Nigella sativa on signs of ocular allergy produced in rabbits by topical application of compound 48/80 Study design: Experimental study Materials and methods: Twelve rabbits were divided in to two groups. Signs of ocular allergy were induced by compound 48/80 and the effect was seen without and with pretreatment with essential oil of Nigella sativa. Results: the findings of present study show that oral pretreatment with Nigella sativa essential oil attenuates the ocular allergic response in rabbits that is produced by compound 48/80. Conclusion: Our findings suggest that Nigella sativa essential oil has mast cells stabilizing property.

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