Nadia Khurshid, Farhan Sadiq, Sameera Akhtar.
Comparison of Efficacy and Morbidity of Pipelle Vs Conventional Endometrial Sampling.
Pak J Med Health Sci Jan ;6(2):388-91.

Objective: To compare the efficacy and morbidity of Pipelle endometrial sampling and conventional D&C sampling in patients with abnormal uterine bleeding and post menopausal bleeding. Study design: Quasi experimental study. Setting: Department of Obstetrics and Gynaecology, Jinnah Hospital, Lahore. Duration: The study was conducted over a period of six months from 07.01.2008 to 06.07.2008 Methods: The study comprised of 100 patients meeting inclusion criteria who were divided into two groups. In group-A, the endometrial sampling was done by Pipelle suction cannula. In group-B, the endometrial sampling was done by conventional dilatation and curettage (D&C). Results: The mean age (±SD) of the study group was 45.4±7.2 years. The most common presenting complaint was menorrhagia (n=45). An adequate sample was obtained in 96% of cases by Pipelle and in 100% of cases by D&C. Both samples labeled as inadequate with pipelle method were polyps.. The procedure related morbidity was negligible in Pipelle sampled group as compared to D&C group. Conclusion: We found that the pipelle is a user and patient friendly device. It is safe and cost effective technique for getting an adequate endometrial sample for histology, with high sensitivity and specificity for detection of hyperplasia and malignancy.

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