Naila Hamid, Shamim Alam, Rashid Mehmood.
Gender differences and prevalence in metabolic syndrome.
J Med Sci Jan ;19(3):141-3.

Objectives: To determine the prevalence and compare the contribution of different components of metabolic syndrome in men and women. Material and Methods: It was a comparative study, including 300 participants, 224 males and 76 females aged 40 years and above. Data was collected from patients of tertiary care hospitals of Khyber Pakhtunkhwa and controls from the general population of the age and sex matched subjects in year 2006. Metabolic syndrome was defined using Third Report of the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III), Asian guidelines and the gender differences of its components were analyzed. Results: Metabolic syndrome was present in 108 (36%) of the study participants more in the middle aged adults. In both women and men a cluster corresponding to the metabolic syndrome representing 49% and 32% of the women’s and men’s sample, respectively. In women, elevated BMI, low HDL cholesterol, increased waist girth and hyperglycemia were significantly (P-value < 0.05) larger contributors to the metabolic syndrome while in men hypertension and elevated triglycerides. Conclusion: The contribution of several metabolic components to the metabolic syndrome is different in men and women. This might contribute to gender specific differences in the relative risk of metabolic complications.

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