Ranjit K Sah, Siddique T, Bhutta Ar, Abdul Latif Sami.
Synovial Sarcoma of Foot: A Case Report.
Ann King Edward Med Uni Jan ;19(2):190-4.

Synovial sarcoma (SS) is a soft tissue tumor with high malignant potential. It is a stem cell malignancy. It is usually found on the extremity. More than 90% of the SS have characteristic translocation i.e. t(X;18) (p11.2; q11.2). Types of SS include monophasic, biphasic and poorly differentiated type. Imaging, histology, immu-nochemical staining and chromosomal analysis is the main modality of diagnosis. Surgery with pre- or post-operative irradiation is the main modality of its treat-ment. However the role of chemotherapy is still con-troversial. 5 - year survival of this locally aggressive tumor is poor. Prognosis depends upon age, size, and histological type of tumor.

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