Muhammad Salman, Muhammad Ayaz Khan, Tamjeed Gul, Muhammad Bilal, Waheed Kamran.
Frequency of Surgical Site Infection in orthopaedic implants surgery with its common bacteria and antibiotic sensitivity.
Pak J Surg Jan ;30(2):167-71.

Objectives: To determine the frequency of Surgical Site Infection and its common bacteria, with antibiotic sensitivity among patients aft er orthopaedic implants surgery. Study design: Descriptive Cross-sectional study. Sett ing& Duration of the study: Orthopaedics and Trauma unit Khyber Teaching Hospital Peshawar from 27th June 2011 to 26th June 2012. Methods: In this study 292 patients with closed fractures of tibia, humerus or neck of femur undergoing internal fi xation by the use of implants (tibial and humerus plating and Austin Moore prosthesis for femoral neck fractures) of any age and gender were included. All the patients received a preoperative dose of broad spectrum cephalosporin (cefazolin) as prophylactic antibiotics at the time of induction of general anesthesia and were continued for 24 hours post-operatively. All the patients were followed up for 30 days post-operatively. Among patients who develop Surgical Site Infection (SSI), wound swab were taken with the help of culture stick for culture and sensitivity. Th e details were recorded in a specialized Proforma and analyzed with SPSS version 17. Results: A total of 292 patients with closed fractures of the tibia, humerus or neck of femur undergoing internal fi xation by the use of implants were included in the study. Surgical site infection was observed in 17 (5.8%) patients. Superfi cial infection was observed in 6 patients while deep infection in 11 patients. Staphylococcus aureus was the most common organism isolated (94%) and E. Coli was cultured in 6% of the cases. Staphylococcus aureus was found to be sensitive to ampicillin, vancomycin, ciprofl oxacin, ceft riaxone, cefotaxime, cefoperazone-salbactum, imipenem, tazobactum and linezolid while E. Coli was sensitive to gentamicin, ciprofl oxacin, levofl oxacin, ceft riaxone, cefotaxime, cefoperazone-salbactum, amikacin, imipenem and tazobactum. Conclusion: Surgical site infection with implants is quite high and needs proper measures to control it. Staphylococcus aureus was the commonest organism isolated from the infected cases.

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