Ruifeng Yang, Zhongmin Jiang, Runqi Zhang, Bing Yu, Xiao Hong Wang, Peng Wang.
Effect of Ligation of the Thoracic Duct During Oesophagectomy on the Absorption of D-xylose.
J Coll Physicians Surg Pak Jan ;27(3):153-6.

Objective: To assess if prophylactic thoracic duct ligation during oesophagectomy influences the absorptive function of oesophageal cancer patients. Study Design: Randomized controlled trial. Place and Duration of Study: Department of Thoracic Surgery, Tai`an City Central Hospital, Tai`an, from August 2014 to December 2015. Methodology: Based on the management of the thoracic duct during oesophagectomy, 60 patients were randomized into two groups. D-xylose absorption test was used to evaluate the absorptive function. The two-independent-samples t-test was employed for statistical analysis with statistical significance at p < 0.05. Results: The serum D-xylose concentration of ligation-group was significantly lower than that of no-ligation group on the first day after operation, (t=2.82, p=0.0066). However, there was no significant differences between them even before operation (t=1.34, p=0.1849). Conclusion: Ligation of the thoracic duct during oesophagectomy immediately affected the absorption of D-xylose, which may lead to malabsorption in the long run.

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