Muhammad Usman Khalid, Muhammad Shahid, Faiqa Saleem Baig, Tipu Sultan.
Effect Of Serum Albumin On Outcome Of Stroke In Children At Tertiary Care Hospitala.
Esculapio J Services Inst Med Sci Jan ;12(4):162-5.

Objective: The objectives of this study were to determine the frequency of favorable outcome of stroke in children presenting at tertiary care hospital and to compare the mean serum albumin levels in children with favorable and unfavorable outcome of stroke in tertiary care hospital. Methods: Two hundred children in the age range of 1-14 years, meeting the inclusion and exclusion criteria were registered from pediatric and neurology department of Children Hospital & ICH Lahore. Informed consent was taken from their parents to include them in the study. Demographic information (name, age, sex, address) was collected. Serum albumin was sent to biochemistry lab of the hospital at the time of admission. Outcome of the stroke was determined by Modified Rankin Scale at the time of discharge and death in case and observed data was recorded on a specially designed proforma (attached). Results: In our study, out of 200 cases, 40% (n=80) cases were between 1-7 years of age, 60% (n=120) cases were between 8-14 years of age, mean±sd was calculated as 7.75±3.49 years, 56% (n=112) cases were male, 44% (n=88) cases were females. Frequency of favorable outcome of stroke in children with stroke presenting in tertiary care hospital was calculated as 42.5% (n=85) while 57.5% (n=115) had unfavorable outcome. Comparison of mean serum albumin levels in children with favorable and unfavorable outcome of stroke in tertiary care hospital showed, 3.13±0.19g/dl in favorable outcome while 1.79±0.18g/dl in unfavorable outcome and p value was calculated as 0.0001 which shows a significant difference between mean serum albumin levels in favorable and unfavorable outcome of stroke. Conclusion: We concluded that most of the pediatric stroke patients have unfavorable outcome and comparatively less patients have favorable outcome of stroke. Also, the mean serum albumin level in children with favorable outcome is higher and it is significantly lower in children with unfavorable outcome of stroke in tertiary care hospital. So higher the serum albumin in pediatric stroke patient one can expect good outcome of stroke.

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