Rahat Jabeen, Ilyas Siddiqi.
Risk Factors of Early Pregnancy Complications.
Ophthalmol Update Jan ;12(3):205-8.

Objective: To determine the underlying risk factors in early pregnancy complications and outcome. Methodology: This case study was conducted at Obstetrics and Gynaecology DepartmentHayatabad Medical Complex, Peshawar from April 2011 to April 2012 after taking permission from local hospital ethical and research committee. All the women with first trimester pregnancy with different complications were included in this study. The inducted women were registered on pre-designed proforma. Data were collected regarding demographic details, gestational period, type of complications, risk factors, treatment and outcome. All data were analysed on SPSS-11, and frequencies were calculated. Chi- square test was used for the assessment of p-values and p-value of <0.05 was considered to be statistically significant. Results: A total of 132 patients with different early pregnancy complications were assessed. Their mean age was 26.5±3.75 years. Commonest complications found were abortion in 93 (70.4%) cases. The underlying risk factors found in abortion were anti-phospholipid syndrome in 7 (7.5%) cases, Diabetes mellitus in 10 (10.7%) cases, hypertension in 19 (20.4%) cases, polycystic ovarian syndrome 13 (13.9%) and infection in 9 (9.6%) cases. Most of the cases 83 (62.8%) were treated by minor surgical procedures, and 31 (23.4%) cases responded with conservative medical therapy. Outcome were anaemia in 83 (62.8%) cases, psychological upset in 79 (59.8%), infection in 45 (34%) cases and coagulopathy in 7 (5.3%) cases. Conclusion: Abortion was found as the most frequent early pregnancy complication and the most frequent underlying risk factor was hypertension. Outcome included anaemia, psychological upset and infection.

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