Sahibzada Nasir Mansoor, Farooq Azam Rathore.
Association Of Rheumatoid Arthritis With Pigmented Villo Nodular Synovitis Of knee: A Case Report.
Khyber Med Uni Med J Jan ;8(2):95-7.

A twenty-one year old male presented to orthopedic surgeon, with severe pain and swelling in right knee joint. He was diagnosed as a case of Pigmented Villo nodular (PVN) on MRI and synovectomy was done. PVN was also confirmed by post-operative histopathology report. He reported for post-surgical knee stiffness and pain at Rehabilitation medicine department. His past history revealed seropositive RA for the past two yearswith poor compliance to medication. The musculoskeletal examination revealed changes in small joints of hands. He was started with tablet methotrexate 7.5 mg weekly along with physical therapy and anti inflammatory medication. The patient gradually improved achieving normal knee range and reduced clinical symptoms of RA within next 03 months. PVN affects the knee joints most of the times. Its exact etiology is unknown. PVN is reported to have an association with Systemic Lupus Erythematosis. Its association with rheumatoid arthritis (RA) is reported only once in literature and require further research.

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