Saleem Sharieff, Khan Shah E Zaman, Khan Shah e Zaman.
Sensitivity and Specificity of Exercise Tolerance Test in patients with chest pain and normal baseline Electrocardiogram.
Pak J Cardiol Jan ;13(3-4):91-5.

Inspite of wide variability of sensitivity and specificity of exercise tolerance test (ETT), this test still is useful for the evaluation of chest pain because of its simplicity and cost-effectiveness. Therefore, we conducted a study to evaluate the sensitivity and specificity of ETT in our population as wells as to risk stratify these patients. A total of 120 patients were included in this study. The mean age was 49.7 ± 10.7 years, male to female ratio was 5.3: 1.0. Abnormal exercise tolerance test (ETT) was found in 70 patients (58.3%) while 50 (41.7%) had normal ETT results. Angiographic evidence of normal coronaries was found in 20.8%, while single vessel coronary artery disease (CAD) was found in 25.8% and multi-vessel CAD in 53.3%. The sensitivity, specificity and test accuracy of ETT in our study was 64.6%, 66.7% and 65%, respectively. Age > 50 years, hypertension, diabetes mellitus, hypercholestrolemia and family history of premature ischemic heart disease (IHD) were the significant risk factors for the development of CAD (p-values = 0.001, 0.011, 0.021, 0.011 and 0.001, respectively).

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