Sarah Riaz, Ejaz Waris, Shahila Jaleel, Bilquis A Suleman.
Correlation of Tumor Size and Grade With Axillary Lymph Node Status in Carcinoma Breast.
Proceeding Shaikh Zayed Postgrad Med Comp Jan ;23(1):29-34.

Objectives: To evaluate the size and grade of carcinoma breast and to correlate these with the axillary lymph node status. Design and place of study: It was a case series observational study conducted in the Department of Histopathology, Shaikh Zayed Hospital, Lahore. Subjects and methods: The study comprised convenient sampling of 30 female patients of age over thirty years undergoing modified radical mastectomy for breast carcinoma during six months from December 2004 to May 2005. Results: In all, 56.25% of cases of tumor size >5cm had >9 axillary nodes positive for metastatic breast carcinoma while 69.2% of grade 3 neoplasms had >9 positive axillary nodes. There was a significant correlation (P <0.01) of tumor size and grade with number of positive nodes. Conclusion: Greater the tumor size and grade, more was the number of axillary lymph nodes positive for metastatic breast carcinoma.

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