Aya Khan, Riaz Ahmad Khan, Bakhtawar Gul Wazir, Asif Khan.
Early Clinical Outcome of Transurethral Resection of Prostate: Pre- and Postoperative Comparison of Symptoms, Flow Rates, Residual Volume and Quality of Life.
J Saidu Med Col Jan ;8(2):122-7.

Background: Bladder outlet obstruction (BOO) in elderly male patients is frequently caused by benign prostatic hyperplasia (BPH) and the problem is increasing as the population is aging. Refined surgical methods are required to optimise clinical outcomes. Transurethral resection of prostate (TURP) has become the standard surgical treatment in BPH. Objective: To assess the clinical outcome for TURP using pre- and postoperative comparison of symptom scores, flow rates, residual volume and quality of life. Material & Methods: The study was conducted at Urology Unit LRH between January 2015 and December 2015. 65 patients with confirmed diagnosis of BPH were prospectively followed for three months after undergoing TURP. Their preoperative international prostate symptoms scores, flow rates, urinary residual volume and quality of life were assessed on initial clinical assessment. The same scores were assessed at the end of third month of follow-up. Results: 65 patients were operated during the study period with a mean age of 64.89 years ± 6.65 SD, the overall outcome was favourable in 52 (80.0%) patients while it was unfavourable in the remaining 13 (20.0%) patients. About 47.7% of patients presented with a history of at least two-years duration. A Wilcoxon signed-rank test determined that there was a statistically significant median improvement of IPSS scores when patients were assessed at the end of follow-up period after undergoing TURP, z = -7.015, p < 0.0005. Conclusions: Postoperative improvement in IPSS scores, postvoidal residual volume, peak flow rates and overall quality of life are significant factors associated with better patient satisfaction. However, surgical results need further improvement.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com