Muhammad Ajmal Khan, Rizwan Sharif, Muzammil Irshad.
Role of Topical Usage of Vancomycin Powder in Prevention of Wound Infection in Spinal Surgery.
Pak J Neuro Surg Jan ;21(1):42-5.

Objective: To determine the efficacy of topical usage of vancomycin powder at wound site to prevent wound infection in spinal surgery.Material and Methods: A prospective study of 62 patients during a period of 6 months with follow-up of 2 weeks post-operatively was performed at Lahore General Hospital Lahore. Patients were divided into two groups: group A and group B, each containing equal numbers of patients. In group A, only prophylactic intravenous antibiotics were used for 5 days. In group B intravenous antibiotics along with topical Vancomycin powder were used at operative site in spinal surgery.Results: During period of follow-up in 2 weeks post-operatively, incidence of wound infection in group A patients was 6.42% in comparison to Group B patients which was 2.4%. No adverse effects were documented by direct usage of Vancomycin powder at wound site.Conclusion: Topical usage of Vancomycin powder at wound site reduces infection rate significantly in spinal surgery.

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