Saeed Ahmad, Tayyeba Rehman, Mariam Safdar, Ayesha Hassan.
Phytochemical Analysis and Tyrosinase Inhibitory Potential of Cassia absus (Seeds).
RADS J Pharm Pharmaceut Sci Jan ;6(2):127-31.

Objective: To perform phytochemical analysis and investigation of the tyrosinase inhibitory activity of Cassia absus seeds.Methods: Various extracts of Cassia absus seed were prepared such as ethanolic extract, n-hexane, chloroform, n-butanol and water fractions.  Tyrosinase inhibitory activity was performed using Kim’s methodology. The extracts were also subjected to phytochemical analysis.Result: Phytochemical analysis showed presence of alkaloids, tannins, flavonoids, glycosides and saponins. Tyrosinase inhibition assay was performed for all the four fractions, n-butanol showed high activity of tyrosinase inhibition (86%) followed by crude ethanol extract (75%) and n. hexane (72%) and water (62%) as compared to kojic acid (97%).Conclusion: From all the results, we found that that phytochemicals present in C. absus seed extract may be responsible for the tyrosinase inhibition activity. The data revealed C. absus seed extracts/fractions could be an addition to medicinal cosmetics.

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