Sohail Bashir Sulehria, Shaukat K, Memon M, Awan A K.
Frequency of Thrombolysis and Comparison of Pericardial Effusion in Myocardial Infarction patients with and without Thrombolysis.
Pak J Med Health Sci Jan ;8(3):747-9.

Aims: To determine the frequency of thrombolysed patients after acute myocardial infarction and to compare the frequency of pericardial effusion in these patients with and without thrombolysis. Methods: This descriptive case series was conducted in East Medical Ward, Mayo Hospital, Lahore for six months. Sample size of 300 cases was calculated and patients were enrolled through non-probability, purposive sampling technique.Informed consent was taken. Frequency of patients that receive thrombolytic agent was calculated. Then patients were divided into Group I, which received thrombolytic agent (streptokinase) and group II, which did not receive thrombolytic agent. Results: Mean age was 55.40±10.28 years. There were 211(70.33%) males and 89(29.61%) females. Out of 300 patients, 160(53.3%) had anterior wall myocardial infarction, while 92(30.7%), 24(8%), 12(4%) patients presented with Inferior wall, posterior wall, lateral wall and infero-posterior wall myocardial infarction respectively. Thrombolytic agent was given to 265(88.3%) patients while 35 (11.7%) did not receive thrombolytic agent. Total 36 patients developed significant pericardial effusion, out of which 12 were from thrombolysed group and 24 from non thrombolysed group i.e. p value=0.0 Conclusion: There are less chances to develop pericardial effusion after thrombolysis with streptokinase as compared to patients in whom thrombolysis is not given.

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