Shamila Ijaz Munir, Shahina Ishtiaq, Shaista Shafiq, Lubna Javed, Tabinda Rana.
Mid Trimester Termination of Pregnancy in women with previous Caesarean Section: a comparison of Misoprostol, PGF2α and Intra-Cervical Foley’s Catheter Traction.
Pak J Med Health Sci Jan ;8(3):554-8.

Aim: To determine the efficacy of oral misoprostol, extra amniotic PGF2α and intracervical Foley’s catheter traction in termination of mid trimester pregnancy in women having previous cesarean section. Methods: All women requiring therapeutic termination of pregnancy between 13 to 26 weeks of gestation having previous cesarean section were included in the study. They were randomized into three groups by lottery method. First group received five doses of oral misoprostol 200μg six hourly, second group received PGF2α extra-amniotically and third group received intracervical Foley’s catheter traction. The expulsion time and complications were noted to determine the efficacy of all three methods in women with scarred uterus. Results: Total 150 women were studied 50 in each group. The success of termination was 82% in misoprostol, 58% in PGF2α and 44% in Foley’s catheter traction which was statistically significant (P=0.000). There was no scar rupture and rate of complications was not statistically significant in all three groups. Conclusion: Misoprostol is safe to be used in mid trimester pregnancy termination and its more efficacious than PGF2α or Foley’s catheter cervical traction.

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