Aamir Mahmood Ijaz, Iqbal H Dogar, Syed M Raza.
Role of Computed Tomography Scan in Establishing a Presumptive Diagnosis in Mediastinal Pathology.
Pak J Med Health Sci Jan ;7(3):592-5.

Aim: To monitor the role of CT scan in establishing presumptive diagnosis in mediastinal pathologies. Study Settings: This descriptive study was undertaken in Department of Chest Surgery, King Edward Medical University/Mayo Hospital Lahore during January 2012 to March 2013. Methods: A total of 135 patients of age 15 and above were registered in this study. Patients were evaluated clinically and history was taken on a pre defined questionnaire. Patients were then asked to have their CT scans done, after which biopsies using various modalities were taken. Findings of the CT scan were then matched with the final histological diagnosis on biopsies. Results: A total 115 out of 135 cases had disease of the anterosuperior mediastinum, 2 out of 135 cases had disease of the middle mediastinum, whereas 18 out of 135 cases had disease of the posterior mediastinum of which 71.3%, 50% and 72.2% respectively showed CT scan picture highly suggestive of a definitive diagnosis as confirmed by the histopathology results. Conclusion: Contrast enhanced CT scan thorax (with densitometry) serves as a valuable diagnostic tool in establishing a presumptive diagnosis in most mediastinal diseases.

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