Syed Ghazanfar Mehdi, Karim Shah Faizi, Rao Saad Ali Khan.
Therapy Induced Anemia in patients with Chronic Hepatitis C Receiving Combination Therapy of Pegylated Interferon Alpha and Ribavirin.
Pak J Med Health Sci Jan ;7(1):204-6.

Aim: To determine the frequency of therapy induced anemia in patients with Chronic Hepatitis C receiving combination therapy of pegylated interferon alpha and ribavirin. Study design: It was a descriptive cross sectional survey. Duration: From Feb 2012 to Sep 2012. Materials and methods: A total of 50 newly diagnosed patients of chronic hepatitis C considered candidates for receiving interferon-alpha and Ribavirin at standard doses for 24 weeks coming to District Headquarter Teaching Hospital, Sahiwal were enrolled. Results: During the study period, majority of the patients were between 41-50 years i.e. 32%(n=16), mean and standard deviation was recorded as 38.33+4.60, 38%(n=19) male patients and 62%(n=31) were found female. Frequency of therapy induced anemia at 2nd week of therapy was 24%(n=12) were found anemic. Conclusion: The frequency of therapy induced anemia in patients with Chronic Hepatitis C receiving combination therapy of pegylated interferon alpha and ribavirin at 2nd week of therapy reveals a significant anemia.

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