Zeeshan Ahmed Qureshi, Zahid Masood, Ayyaz Ahmed, Nuzhat Navid.
Efficacy of Daptomycin against Clinical Isolates of Methicillin Resistant Staphylococcus Aureus (MRSA).
Pak J Med Health Sci Jan ;12(2):517-8.

Aim: Efficacy of daptomycin against clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) from surgical ward in a tertiary care hospital. Study Design: Descriptive study . Place Of Study: Department of microbiology, Armed Forces institute of Pathology, Rawalpindi, from November 2013 to November 2014. Methodology: MRSA isolates from various clinical samples were included in the study. API-staph was used to confirm MRSA. Susceptibility of MR SA against daptomycin was performed by E-strip method. The results were interpreted as recommended by Clinical Laboratory Standard Institute (CLSI) guidelines. Results: Maximum number of MRSA were isolated from pure pus i.e. 67.6%. Total of 170 isolates were included in the study. We found resistance of MRSA against daptomycin in 03 (1.8%) cases. Conclusion: Few number of isolates resistant from daptomycin, are at present not a threat. But in future this may create treatment problems.

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