Muhammad Munir Ahmed, Rahat Sarfraz, Arshad Munir Gondal.
To study the Blood Lead Levels and Weights of Albino Mice in Different Doses of Lead.
Pak J Med Health Sci Jan ;12(2):519-20.

Aim: To study the blood lead levels and weights of albino mice in different doses of lead. Methodology: 36 albino mice were divided into three groups. Group A (control) was fed on synthetic diet, groups B and C were given lead acetate 2 mg and 8 mg/kg/day respectively for 60 days. Weights were recorded after 60 days and blood lead levels were done by taking blood in EDTA vials. Results: The weights of different groups were measured at 60 days and the mean +- SD values of weights in group A to C were 33.8 +- 2.8, 33.5 +- 3.9 and 29.95 +- 5.5gms respectively and comparison between A Vs B showed non- significant difference (p>0.05) while comparison between groups A vs C and B vs C showed statistically significant difference (p<0.05). No significant difference was seen in blood lead levels of group A (control) at 60 days duration while Group B and C showed significant increase in the blood lead level at 60 days duration (p<0.01) as compared with control group. Conclusion: Group B and C showed significant increase in the blood lead level at 60 days duration (p<0.01) as compared with control group.

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