Ayesha Muneer, Attia Bari, Nousheen Fatima, Fatima Tahira, Hammad Riaz, Agha Shabbir Ali.
Maternal Vitamin D Status Reflects Vitamin D Status of Preterm and Full-Term Neonates.
Pak Paed J Jan ;42(2):110-4.

Aims & Objective: To measure neonatal and maternal 25-OH vitamin D serum levels and to assess the correlation between maternal and newborn serum levels of vitamin D in preterm and full term newborns. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Neonatal department of Lahore General Hospital from Jan 2017 to July 2017. Material and Methods: Total of 90 mothers and 90 babies were included in the study. Forty-five babies were preterm while 45 were full term. Blood samples were collected from mothers and their full term and preterm newborns admitted in the neonatal section or visiting out-patient department. Serum 25-hydroxyvitamin D concentrations were measured. Results: Mean maternal age was 26.73 ? 4.14 years and newborn age 2.99 ? 0.80 days. Mean maternal vitamin D level was 22.37 ? 14.17 nmol/L (normal value:77-250 nmol/L). Forty seven percent of mothers had vitamin D deficiency, 34% had vitamin D insufficiency. Mean newborn vitamin D level was 16.80 ? 10.20 nmol/L. Among the newborns 63% were vitamin D deficient and 37% had insufficient levels. Preterm newborns were more vitamin D deficient/insufficient 88.9% as compared to full term babies 73.3% (p=<0.001). Low maternal vitamin D levels were significantly associated with low newborn vitamin D Levels (p=0.004). Conclusions: Serum vitamin D level of <30 nmol/L was widespread in parturient women. Poor maternal vitamin D status adversely affect neonatal vitamin D status. Optimizing maternal vitamin D status during pregnancy and improving postnatal vitamin D intake may enhance infant vitamin D status.

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