Naveed Ali Siddiqui, Saida Haider, Mohammad Misbah-ur Rehman, Tahira Perveen.
Role of herbal formulation of garlic on lipid profile in patients with type 2 diabetes related dyslipidemia.
Pak Heart J Jan ;49(4):146-50.

Objective: To evaluate the role and side effects of garlic on lipid profile in diabetic dyslipidemic patients along with their lipid lowering efficacy. Methodology: This cross sectional study was carried out at Surgeon Munawar Memorial Hospital Bahadurabad Karachi. The study period consisted of 8 weeks from 1 February 2015 to 31 March 2015. Patients with age between 30 and 60 years of either gender with diabetic dyslipidemia were included . The exclusion criteria included pregnant/lactating females, liver, renal and established coronary artery disease or ischemic heart disease. Results: Total of 30 diabetic dyslipidemic patients with abnormal lipid profile were included. Patients were orally administered with local herbal product of garlic (300 mg/day) for 8 weeks. Serum levels of cholesterol, high density lipoprotein (HDL), triglyceride (TG), and low density lipoprotein (LDL) were estimated in patients before and after treatment with local herbal product of garlic(300 mg/day). After the treatment of garlic, serum cholesterol and low density lipoprotein were significantly decreased but there was no effect on triglyceride levels (p >0.05). Conclusion: On the basis of this study we concluded that herbal products like garlic significantly decreases cholesterol, low density lipoprotein (LDL) and increases high density lipoprotein (HDL).

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