Kashif Javed, Nauman Ali, Mubasher Sherwani.
Comparison of outcome of patients having first acute myocardial infarction with or without pre-infarct angina.
Pak Heart J Jan ;48(2):107-10.

Objective: To compare outcome of patients having first acute myocardial infarction with or without pre infarct angina. Methodology: This cross sectional study was done in department of cardiology in Chauhdary Pervaiz Elahi Institute of Cardiology Multan. Patients of acute myocardial infarction (divided in two equal groups) were included in the study.Based on the history of pre-infarct angina, patients were stratified into two equal groups; group A patients who had pre-infarct angina and group B with no angina .Patients were admitted in the coronary care unit and were monitored with ECG for rhythm abnormalities, echocardiography for left ventricular systolic dysfunction and in-hospital mortality. Results: There were 200 patients included in this study. Mean age of the patient population was 52.51 +- 6.37. There were 125 (62.5%) males and 75 (37.5%)females. Systolic dysfunction was identified in 6% in group A and 29% in group B(p < 0.0001, Odd's ratio of 6.399), arrhythmia in 12% patients in group A and 33% in group B (p = 0.001, Odd's ratio of 3.612), mortality was present in 5%patients in group A and in 15% in group B (p = 0.032 and an Odd's ratio of 3.353). Conclusion: Pre-infarct angina was associated with an improved outcome inpatients with first MI as compared to those patients who never experienced angina. This improved outcome was significant in all the three variables which we studied, i.e. arrhythmias, systolic dysfunction and mortality.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com