Muhammad Musharaf, Iqbal Hussain Pathan, Sanaullah Junejo, Muhammad Jawad, Khalas Khan Niazi.
Surgical revascularization in ischemic cardiomyopathy with fixed perfusion defect.
Pak Heart J Jan ;48(2):90-5.

Objective: The object of study was to evaluate our six years data of surgical revascularization in ischemic cardiomyopathy. Methodology: This descriptive cross sectional study was conducted at National Institute of cardiovascular diseases Karachi from January 2007 to January 2014.Patients were followed for 6 months. All the patients with Ischemic Cardiomyopathy who underwent coronary artery bypass grafting and had a preoperative left ventricular ejection fraction less than or equal to 35% were included. Left ventricular ejection fraction was determined by transthoracic echocardiography. Indication for surgery was predominance of anatomical nature of coronary artery disease. Functional improvement was evaluated through NYHA class improvement. Results: A total of 34 patients were included in this study. There were 22 (64.7%)males and 12 (35.3%) females with mean age of 69.3 years. An average of 2.9 +-0.67 coronary bypass grafts per patient were performed. In-hospital mortality was 14.7% (5 patients). The 6 month survival rate was 92.8%. While NYHA class improvement was observed in 52.9% of survivors at six month. Conclusion: In selected patients with severe ischemic left ventricular dysfunction and no tissue viability, coronary artery bypass grafting is high risk procedure.Improvement in functional class was documented in survivors. CABG may be considered in ischemic cardiomyopathy in selected cases.

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