Shah Zeb, Mohammad Hafizullah, Akhtar Sher, Hisar.
Mvp: a clinical and echocardiographic experience of mitral valve prolapse in Khyber Pakhtoonkhwa.
Pak Heart J Jan ;47(2):100-5.

Objective: To study the clinical presentation and echocardiographic findings in patients having mitral valve prolapse. Methodology: This observational study was conducted in cardiology department LRH Peshawar, from December 2012 to March 2013. All patients with echocardiographic evidence of mitral valve prolapse were included in the study. Their clinical presentation and echo cardiographic characteristics were studied. Results: A total of 142 patients have echocardiographic evidence of mitral valve prolapse were included. Their mean age was 19.45+-7.32 years. Males were 57(40.14%). The most frequent symptoms were palpitation in 128(90.14%), chest pain in 111(78.16%), dizziness and vertigo in 103(72.34%).Mean BP was 101.34+-14.32 mmHg systolic and 60.24+-15.87 mmHg diastolic. Mean pulse rate was 82.46+-18.74 per minute. Midsystolic ejection click was found in 79(55.63%), late systolic murmur in 47(33.08%), pansystolic murmur was observed in 7(4.9%). AF was found in 19(13.38%) and complete RBBB in 11(7.74%). Echo findings were having thin leaf mitral valve(Non Classic MVP) in 113(79.58%) and thick leaflet(classic MVP) in 29(20.42%).Severe mitral regurgitation in 8(5.6%), severe PAH 2(1.4%), Mean LA size was 4.13+-1.3cm, Mean Left ventricular end diastolic diameter (LVEDD) was 5.13+-1.4cm, Mean Ejection Fraction(EF) was 60.45+-6.8%. Mean age of patients having classic MVP(29(20.42%)) was 31+-7.8 years, 10(34.48%) have AF, 6(20.69%) have severe MR, 2(6.9%) have severe PAH ,mean LA size was 4.52+-1.7cm, mean LVEDD was 5.56+-2.1cm and mean EF was 53.76+-8.5%. Conclusion: Nonclassic MVP is more frequent than classic form. Patients with classic MVP is more often have older age, severe MR and ECG findings of arrhythmias than non classic form.

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