Muzaffar Ali, Sayem Ahmad, Usman Butt, Ahsan Iqbal, Zubair Akram.
Assessment of regional left ventricle systolic function by doppler strain imaging in hypertensive patients.
Pak Heart J Jan ;47(1):34-8.

Objective: The objective of study was to evaluate regional myocardial function by strain (S) echocardiography in patients with or without diastolic dysfunction and healthy individuals with normal left ventricular ejection fraction. Methodology: This cross-sectional comparative study was conducted at department of cardiology, Jinnah Hospital Lahore, from January 2012 to October 2012. Thirty hypertensive and thirty healthy individuals were enrolled in study. Strain Doppler echocardiography was used to evaluate 30 patients with hypertension and 30 age matched control subjects. With pulsed-wave Doppler, mitral inflow velocities were obtained to measure diastolic E and A waves, E/A ratio, and E-wave deceleration time (DT); with tissue doppler imaging early diastolic (Ea), and late diastolic velocities (Aa) and longitudinal peak systolic strain (S ) values were measured. Results: Mean age of study population in control subjects (Group A) 45+-6 years and in hypertensive subjects (Group B) 53+-7 years. Among control subjects, 18 were males (60%) and 12(40%) were females. In hypertensive subjects 16(53.3%) were males while 14(46.6%) were females. No difference was noted regarding age, sex, body surface area and heart rate. Among the hypertensive patients, 14(46.6%) were having diastolic dysfunction while 16(53.3%) patient were without diastolic dysfunction. Peak strain values were significantly decreased in patients with hypertension with or without diastolic dysfunction as compared to healthy individuals. Conclusion: Hypertensive patients with or without diastolic dysfunction have reduced left ventricular systolic longitudinal strain.

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