Imran Khan, Saira Gull, Junaid Fayyaz Khan, Zafar Tufail, Kamran Khan, Abdul Waheed.
Mitral valve repair for ischemic mitral regurgitation: experience at a tertiary care hospital.
Pak Heart J Jan ;46(4):260-4.

Objective: To know the outcomes of mitral valve repair for ischemic mitral regurgitation and its medium term survival. Methodology: This retrospective study was carried out at a tertiary care hospital. All those patients who underwent mitral valve repair for ischemic mitral regurgitation between January 2007 and January 2009 were included in the study. Patients were followed at regular 3 monthly intervals and time related survival curves developed using Statistical Package for Social Sciences. Mortality was considered as the primary outcome during the follow up period. Results: A total of 19 patients (n=19) with a mean age 53.84+-6.85 years underwent repair for mitral valve for ischemic regurgitation. These included 13(68.4%) male patients while 6(31.6%) were females. All the patients had moderate to severe mitral regurgitation on echocardiography preoperatively. All the patients underwent concomitant Coronary Artery Bypass Grafting. The in hospital stay was 19.79+-4.35 days with no in hospital mortality. Patients were followed up for 36 months. During followed up, 2 (10%) patients died, one at 25th month and the other at the 35th month both due to heart related causes. A Cox regression model showed age [OR=1.185, (95%CI, 0.994 to 1.412, p=0.058)], low EF [OR=1.02, (95% CI,0.897 to 1.157, p=0.773)] and longer cross clamp time [OR=1.05, (95% CI, 0.763 to 121.723, p=0.351)] to be predictors of mortality. Conclusion: Repair for mitral regurgitation post myocardial infarction can be undertaken with acceptable mortality and provides good medium term results. The repair should be done whenever the adjacent tissue is not diseased and friable.

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