Muhammad Ilyas, Farooq Ahmad, Muhammad Abdur Rauf, Syed Farhat Abbas Shah, Muhammad Hafizullah.
Correlation of left atrial volume with e/e` ratio among patients presenting with diastolic dysfunction.
Pak Heart J Jan ;46(2):127-32.

Objective: To determine the association between left atrial volume and E/+- ratio among patients with diastolic dysfunction. Methodology: All male and female patients of age > 40years with clinical diagnosis of heart failure were included in the study. Detailed echocardiographic study was performed with Accoson CV 70. Patients with normal ejection fraction and diastolic dysfunction on TDI with E/+->15 were looked for LA volume using modified Simpson method. Results: Total of 82 patients with a mean age of 60.4 +- 9.916years were included among them 56% (n-46) were male. Using Tissue Doppler Imaging for diastolic function patients were stratified into three groups on the basis of E/A ratio. Group 1 (E/E` ratio of 16-18), group 2 (E/+- ratio of 19-21) and group 3 (E/E` > 21). Overall mean E/E` ratio was 18.45 +- 2.10 while mean LA volume was 69.80 +- 9.16ml. Comparing LA volume men had mean LA volume of 71.9 +- 9ml while women had 67.8 +- 9ml and the mean E/+- was 18+-5 for men versus 18+-3 for women. Mean LA volume in group I, group II and group III were 65.8ml, 72.6ml and 80 ml respectively. There was a significant correlation between E/E` & LA volume using pearsons correlation (r= 6.08 & PL< 0.001). Conclusion: There is a linear association between LA volume and E/E` ratio. LA volume increases progressively with increasing severity of diabetic dysfunction.

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