Jawad Hussain Qamber, Farooq Khan, Saadia Sajjad, Mussarat Bano, Fakhar Un Nisa, Bushra Gohar Shah.
Assessment of Circulating Blood Lipid Profile Markers in medical students during/ after exam stress.
Pak J Med Health Sci Jan ;12(3):1132-5.

Background: Stress of examinations is a factor that affects many organ systems of our body. A relation exists between stress and Physiological and Biochemical markers. Aim : Assessment of the level of blood Lipid profile in medical students during and after examinations. Methods : This cross sectional study was conducted at the department of Physiology, The university of Lahore from January 2013 – February 2013. Sixty healthy medical students planning to take their professional exam were recruited. Students with health behaviors or health problems that may alter immune oxidative stress measures were excluded from the study. Study participants reached at the laboratory in morning hours (7-11 am) in fasting state in the week preceding annual examination. Then the second visit was scheduled a month or more (4-7 weeks) after the examination. Fasting blood samples were obtained to be used in evaluation of Lipid profile . Results: Out of these sixty subjects, 23 were males and 37 were females. Their age ranged from 19 to 21 years. Significant difference was observed in the values of total cholesterol (TCh ), triglycerides (Tg ), low density lipoproteins( LDL ) and high density lipoproteins (HDL) during stressed (Phase-I) and relaxed phase (Phase-II). Levels of TCh, Tg and LDL were raised during the stress state while The level of HDL during the Phase-I was decreased as compare to the Phase-II. The differences between the stressed and relaxed state were significant Conclusion: Stress of examination affects the levels of Lipid profile markers significantly .

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