Saeed Khan, Bakhtiar Ullah, Siddique Ahmad, Rizwan Ahmed Khan, Ssadiq Jafri M Mussadiq, Amir Zeb.
Comparison of open versus laparoscopic cholecystectomy for gall stone disease: Our experience at Hayatabad Medical Complex.
Pak J Surg Jan ;36(2):121-5.

Objective of study: To compare the "Outcomes of open versus laparoscopic cholecystectomy: Our experience at Hayatabad medical complex, Peshawar" in the management of gall stone disease Material and Methods: A randomized clinical trial study performed for the comparison of open and laparoscopic cholecystectomy at department of surgery, Hayatabad Medical Complex (HMC), Peshawar. We recruited 80-patients above the age of 40-years with gall stone disease. Patients were randomised into 2-treatment groups. For all the patients intra-operative cholangiography was done. Operating time, post-operative complications, and length of hospital stay were reported. All the data were entered and analyzed through SPSS version 20. Post-stratification the chi-square test was applied and p-value <=0.05 considered as significant. Results: A total of 80-patients were selected for the study, who presented with gall stone disease and were suitable candidates for cholecystectomy. Mean age of group-A was noted 48+-2.5 years and group-B reported 51+-3.4 years. Gender distribution was found as: group-A contains 22 (55%) male participants and 18 female participant and group-B contains 24 (60%) male participants and 16 female participants. The mean operative time was 75 minutes for Open Cholecystectomy and 86 minutes for Laparoscopic Cholecystectomy, which is statistically significant difference i.e. P<0.001. The statistically significant difference also found in the hospital stay between the group P<.001. Conclusion: We conclude that laparoscopic cholecystectomy is safer and valid alternate procedure to open cholecystectomy for patients with gall stone disease. Laparoscopic cholecystectomy has low complications rate, shorter hospital stay and provide more comfortable post-operative period as compare to open cholecystectomy.

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