Rabia Sattar, Ghazal Mansoor, Sana Qanber Abbasi, Qurat-ul Ain, Sana Javid, Nazish Jamil.
Hemoglobin Evaluation in Hypertensive Disorders of Pregnancy.
J Dow Uni Health Sci Jan ;15(1):10-6.

Objective: To evaluate the maternal hemoglobin (Hb) concentration and its levels in hypertensive pregnant patients during the third trimester of gestation. Methods: A prospective cross-sectional study was conducted in an Obstetrics and Gynecology department of teaching hospital affiliated to The University of Lahore from November 2017 to June 2018. All pregnant women aged 18-40 years having third trimester of gestation, who came for antenatal check up or admitted to hospital were consecutively included. The demographic characteristics of pregnant women were documented and Hb concentration was assayed in the hematology laboratory and evaluated in pregnant females with hypertension (Hypertensive pregnant group) and healthy normotensive pregnant women. Hypertensive pregnant group were further categorized as pregnancy induced hypertensive (PIH), pre-eclampsia, and eclampsia. Results: Of 78 pregnant women (62 hypertensive and 16 normotensive), the median age was 25 (23–29) years. Of 62 hypertensive women, PIH was observed in 33 (42.3%) women, pre-eclampsia in 17 (21.8%), and eclampsia in 12 (15.4%). The median HB level was observed in 11.5 (10-12) g/dL. The median Hb level in normotensive pregnant women was significantly higher as compared to hypertensive pregnant women, i.e., 11.9 (11.6-12.0) vs. 11.0 (9.5-12.0) respectively (p-value 0.006). Furthermore, among hypertensive women, the median Hb level was insignificantly higher in eclamptic women [11.5 (11.1-12.0)] as compared to PIH [10.7 (9.4-12.2)] and pre-eclamptic women [9.9 (9.5-11.7)] (p-value 0.079). Conclusion: In the present study, the evaluation of Hb shows a statistically significant deterioration in Hb levels among hypertensive pregnant patients as compared to normotensive pregnant women.

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