Madiha Arshad, Shahida Niazi.
Breast Phyllodes Tumor: a 6-year Retrospective Series Analysis at Mayo Hospital/King Edward Medical University, Lahore, Pakistan.
J Sharif Med Dent Coll Jan ;5(2):65-70.

Objective: This study was conducted to determine the frequency and salient pathological features of the different subtypes of phyllodes tumors (PT) at Mayo Hospital/King Edward Medical University, Lahore, Pakistan. Methodology: It was a cross-sectional study conducted at the Histopathology Section of the Pathology Department of Mayo Hospital/King Edward Medical University, Lahore, Pakistan. The study was approved by the ethical committee of the institution. The histopathological records of 30 patients with a diagnosis of PT reported in 6 years from 1st January 2013 to 31st December 2018 were reviewed. The tumors were categorized into benign, borderline and malignant subtypes based on the World Health Organization (WHO) criteria. Other parameters analyzed were the age at the time of presentation, tumor size, tumor laterality, the type of surgical specimens received, the status of surgical margins and recurrence of the tumor. The Statistical Package for the Social Sciences (SPSS) version 24 was used for analyzing the data. Results: Out of 30 cases, there were 15(50%) cases of benign PT, 6(20%) cases were classified as borderline and 9(30%) cases were placed in the malignant category. The age of the patients ranged from 25 to 80 years with a mean of 41.07 11.13 years. The size of the tumors ranged from 4-22 cm with a mean of 10.53 4.13 cm. The surgical specimens comprised of 2(6.67%) wedge biopsy samples, 20(66.67%) lumpectomy specimens, 4(13.33%) simple mastectomy and 4(13.33%) cases of modified radical mastectomy specimens. These specimens included 4(13.33%) recurrent cases of phyllodes tumor. Conclusion: Our study concluded that benign phyllodes tumor was the most common type (50%) of phyllodes tumor followed by malignant category (30%). Recurrence of the tumor was reported in 4(13.33%) cases. All 3 subtypes of phyllodes tumors are prone to recurrences so wide surgical excision is the preferred therapy. Keywords: Phyllodes tumor. Breast tumor. Lumpectomy. Mastectomy. Wide surgical excision.

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