Haris Tariq Chohan, Arun Kumar, Muhammad Imran Riasat, Muhammad Imran Khan, Syed Farjad Sultan, Safia Zafar Siddiqui.
Comparison of Effectiveness of Intravenous Paracetamol and Tramadol for Post Adenotonsillectomy in Children.
J Surg Pak Jan ;25(3):117-21.

Objective: To compare the effectiveness of intravenous paracetamol and tramadol for post adenotonsillectomy in children when given as a single bolus dose. Study design: Randomized controlled trial. Place & Duration of study: Department of Anesthesiology, Surgical ICU and Pain Management, Dr. Ruth K M Pfau Civil Hospital Karachi (CHK), from November 2017 to April 2018. Methodology: Patients operated electively for adenotonsillectomy between the age of 6 years to 18 years were included in this study. They were randomly allocated into two groups. In group A patients were treated with intravenous paracetamol 15 mg/kg, 15 minutes after induction of general anesthesia. In group B intravenous tramadol 1 mg/kg was given 15 minutes after the induction of general anesthesia. At the end of surgery patients were extubated and transferred to recovery room and monitored. All patients received 4 - 5 liter/minute oxygen via a face mask. After two hours of analgesia dose, postoperative pain was assessed with the help of VAS (Visual Analogue Score). Results: A total of 60 patients were included, with 30 patients in each group. The mean age of the patients in group A was 12.97+-3.39 year and group B 12.80+-3.19 year. There were 31(51.7%) males and 29 (48.3%) females. Pain relief was significantly high in group B as compared to group A (86.7% vs. 56.7% - p=0.010). Conclusion: Intravenous tramadol was better than intravenous paracetamol for postoperative analgesia after adenotonsillectomy in children.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com