Arosha Mansoora Khan, Abdul Latif Khattak, Mohammad Shabaz Amin, Mohammad Anwar, Faisal Mehmood, Mohammad Khalid Azam Khan.
Frequency of thyroid dysfunction in patients with CLD (chronic liver disease) secondary to hepatitis C virus.
Pak J Pathol Jan ;32(3):116-9.

Objectives: To establish the rate of thyroid dysfunction in patients with CLD resultant from HCV (Hepatitis C Virus). Material and Methods: This descriptive, cross-sectional study was held in Medicine Department in CMH (Combined Military Hospital), Kohat from 3rd January 2020 to 2nd July 2020. One hundred patients of chronic HCV causing CLD were selected for the study. Age ranging 18 - 65 years of either gender were included. Patients taking medication that can affect thyroid functions, known thyroid disorders and CKD (Chronic Kidney Disease) were not selected. Blood samples were sent to the laboratory to assess thyroid function tests and thyroid dysfunction was noted. Results: Age ranging 18 - 65 years with mean age of 37.69 +- 8.72 years. Majority patients 56 (56%) were ranging 18 - 40 years of age whereas 44 (44%) were from 41 - 70 years of age. Out of the 100 patients, 45 (45%) males and 55 (55%) females with ratio 1.1: 4 respectively. Frequency of thyroid dysfunction in patients of CLD from HCV was found in 4 (4%) patients with 01 was hypothyroid and 03 were hyperthyroid. Conclusion: This study concluded that rate of thyroid disease in CLD patients affected from HCV is not too high in our study.

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