Bakht Samar Khan, Abid Nawaz, Imran Ahmad, Zaman Shah.
Measuring Loss of Corneal Endothelial Cell Density and Retinal Nerve Fiber Layer Thickness in Primary Open Angle Glaucoma..
J Saidu Med Col Jan ;11(3):137-41.

Background: Primary open angle glaucoma is an irreversible disease causing a reduction in corneal endothelium cells mainly responsible for corneal clarity along with nerve fiber layer loss. Objective: To calculate loss of corneal endothelium density (CED) and retinal nerve fiber layer(RNFL) thickness in Primary open angle glaucoma(POAG).Material and Methods: It was a prospective observational study conducted in Khyber Teaching Hospital from April 2015 to December 2019. A total of 112 patients were included in the study through consecutive non-probability sampling technique. Patients were diagnosed with open angle glaucoma on the basis of intra ocular pressure (IOP), optic disc changes, visual fields changes and Optical coherence tomography (OCT) findings. Corneal endothelium density and thickness of retinal nerve fiber layer was calculated on the basis of specular microscopy and OCT. These were compared with normal matched values. Results: The POAG patients have average 17.12% CED and 34.73% RNFL thickness loss. Conclusion: It is observed that Corneal endothelial cell count may be evaluated along with nerve fiber layer thickness in Primary open angle glaucoma. Keywords. Specular microscopy, OCT, RNFL,POAG.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com