Muhammad Tariq Khan, Muhammad Ilyas, Salman Khan, Jawad Ahmad Kundi, Fariha Kifayat.
Effect of Local Anesthesia with 1:100,000 Epinephrine on Glycemic Level of Type II Diabetic patients Undergoing Oral Surgery.
J Saidu Med Col Jan ;11(4):181-4.

Background: The rate of type II diabetic patients is increasing and results in oral manifestations. The oral surgery needs extraordinary measures in these patients. Objective: To assess the effect of anesthetic agent with 1:100,000 epinephrine and without epinephrine in the blood glucose level of diabetic patients. Material and Methods: This was a randomized study of 60 patients having type 2 diabetes mellitus who were undergoing tooth extraction. The study was double blind. 30-70years aged patients were selected. Blood glucose level was monitored 15 minutes before giving local anesthesia and after 20 minutes of the injection. ANOVA was used for comparison between groups. Results: No significant difference was seen in glycemic level using local anesthesia with 1:100,000 epinephrine (p=0.345). There was slight decrease noted in the blood glucose level of both groups. Conclusion: The use of 2% local anesthesia with 1:100,000epinephrine didn't cause hyperglycemia in diabetic patients. Keywords: Diabetes Mellitus, Local Anesthesia, Epinephrine, Tooth Extraction, Lidocaine.

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