Ahmed Suhag, Shazia Begum Shahani, Umbreen Bano, Pashmina Shaikh, Gunesh Kumar, Asad Ali Zardari.
Airway Resistance and Conductance in Adults with Central Obesity.
Pak J Med Health Sci Jan ;15(2):913-6.

Objectives: To study airway resistance and specific airway conductance using body plethysmograph and to determine the pulmonary function tests in adults with central obesity and to relateby age and gender with controls. Study Design: Cross-sectional study Place and Duration of Study: Methodology: Eighty non-smoking adults in the age group of 20-40 years were enrolled. The study group included 40 subjects with a waist circumference >=90 cm in men while >=80 cm in women. Forty age and gender-matched subjects with waist circumference <90 cm in males and <80cm in females were selected as controls. Raw, Saw, FVC, FEV1, FEV1/FVC, PEFR and FEF25-75 were noted in both the groups using MEC PFT body plethysmograph. Results: FVC (P-value = 0.04) and FEV1 (P-value = 0.03) were significantly reduced in subjects with central obesity when compared to controls. FEV1/FVC ratio, PEFR, and FEF25-75 did not varyconsiderablyin-between 2 groups. Airway resistance (P-value = 0.02) was found to be significantly high in the study group compared to controls. But, specific airway conductance was comparable between the two groups. Conclusion: Subjects with central obesity showed a decline in lung functions in a restrictive pattern. Keywords: Airway resistance, Body plethysmography; Central obesity

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